| MPO和CD24在食管癌组织中的表达及相关性研究 |
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| 引用本文： | 黄波,王燕颖,艾迎春,邱冰,张沛怡.MPO和CD24在食管癌组织中的表达及相关性研究[J].现代生物医学进展,2013(22):4275-4277,4397. |
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| 作者姓名： | 黄波 王燕颖 艾迎春 邱冰 张沛怡 |
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| 作者单位： | [1]佳木斯大学附属医院消化科,黑龙江佳木斯154007 [2]黑龙江省医院消化科,黑龙江哈尔滨150030 [3]大庆铁人医院,黑龙江大庆163413 |
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| 基金项目： | 黑龙江省留学回国人员科技项目（200923）; 黑龙江卫生厅科研课题（2011652） |
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| 摘 要： | 目的：探讨MPO和CD24在食管癌组织中的表达及其意义。方法：通过免疫组织化学染色法检测食管癌组织及Barrett食管组织中MPO和CD24的表达及其相互关系。结果：MPO和CD24阳性表达在食管癌组织中为（80.39%,45.09%）,均显著性高于Barrett食管组织（62.74%,14.28%）,其差异有统计学意义（P〈0.01）。MPO和CD24在食管癌组织中表达有正相关性（r=0.29,P〈0.05）。结论：MPO和CD24可能参与了食管癌的启动及发生过程,在食管癌的发生、发展和转移过程中起着重要作用。
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| 关 键 词： | 食管癌 Barrett食管 CD24 MPO 免疫组化 |
A Study on Expressions of and Correlation Between MPO and CD24 in Esophageal Tissues |
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| HUANG Bo;WANG Yan-ying;AI Ying-chun;QIU Bing;ZHANG Pei-yi.A Study on Expressions of and Correlation Between MPO and CD24 in Esophageal Tissues[J].Progress in Modern Biomedicine,2013(22):4275-4277,4397. |
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| Authors: | HUANG Bo;WANG Yan-ying;AI Ying-chun;QIU Bing;ZHANG Pei-yi |
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| Institution: | HUANG Bo;WANG Yan-ying;AI Ying-chun;QIU Bing;ZHANG Pei-yi;Digestive dept. of Jiamusi university hospital;Tieren in Daqing hospital;Digestive dept. of Heilongjiang province hospital; |
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| Abstract: | Objective： Explore the MPO and CD24 expression in esophageal cancer tissue and its significance.Methods： MPO and CD24 expression and their relationship in esophageal tissue and Barrett＇s esophagus tissue by chemical staining immunohistochemistry.Results： MPO and CD24 positive expression in esophageal cancer tissues（80.39%,45.09%）,significantly higher than that of Barrett＇s esophagus tissue（62.74%,14.28%）,the difference was statistically significant（P0 01）.MPO and CD24 expression in esophageal cancer tissue has a positive correlation（r=0.29,P0.05）.Conclusions： MPO and CD24 may be involved in the process of esophageal start and play an important role in the occurrence,development and metastasis of esophageal cancer. |
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| Keywords: | Cancer of the esophagus CD24 MPO Immunohistochemical |
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