Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm, S-104 05 Stockholm Sweden;Department of Bacteriology, National Bacteriological Laboratory, S-105 21 Stockholm Sweden
Abstract:
Escherichia coli C is an R-strain, and hence its lipopolysaccharide consists only of lipid A joined to a basal core. Intact core-polysaccharides have been prepared from this strain, and from mutants of the same strain defective in various stages of core biosynthesis. Using sugar and methylation analyses, and chemical and enzymic degradations, the hexose region of the core of the parent strain has been shown to be a pentasaccharide for which the following structure is proposed:
