Cell differentiation inducers derived from thalidomide |
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| Authors: | Noguchi Tomomi Miyachi Hiroyuki Katayama Ryohei Naito Mikihiko Hashimoto Yuichi |
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| Institution: | Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. |
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| Abstract: | 5-Hydroxy- and 4-amino-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione (5HPP-33 and 4APP-33, respectively) have been shown to possess cell differentiation-inducing activity toward human leukemia cell line HL-60. |
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