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The role of nutrition in viral disease |
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| Authors: | Melinda A. Beck |
| Affiliation: | a University of North Carolina at Chapel Hill, Department of Pediatrics, 105 Smith Level Road, CB No. 8180, Chapel Hill, NC, USA b The Frank Porter Graham Child Development Center, 105 Smith Level Road, CB No. 8180, Chapel Hill, NC, USA |
| Abstract: | Malnutrition has been associated with a decrease in immune function. Impairment of immune function may lead to increased susceptibility to infection with viruses. Although there are many studies documenting the effect of host nutritional status on immune functions, fewer studies have examined the effect of host nutritional status on viral pathogenesis. This review examines the relationship between viral infection and the nutritional status of the host, and documents that not only can the nutritional status of the host affect immune function, but can have profound effects on the virus itself. One mechanism by which nutritional status affects the virulence of the viral pathogen involves selection for virulent viral genotypes. Other mechanisms remain to be elucidated. |
| Keywords: | Author Keywords: virus malnutrition nutrient deficiency viral infection |
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