Role ofCandida in indirect pathogenesis of antibiotic associated diarrhoea in infants |
| |
| Authors: | K. M. Ponnuvel R. Rajkumar Thangam Menon V. S. Sankaranarayanan |
| |
| Affiliation: | (1) Department of Microbiology, Dr. ALM. P.G. Institute of Basic Medical Sciences, 600 113 Taramani, Madras, India;(2) Institute of Child Health and Hospital for Children, 600 008 Egmore, Madras, India;(3) Molecular Biology Lab, Central Sericultural Research and Training Institute, 570 008 Srirampura, Mysore, India |
| |
| Abstract: | One hundred and thirty seven isolates ofCandida species were isolated from antiobiotic associated diarrhoea cases and were examined to study the role ofCandida in the pathogenesis of diarrhoea in infants. The quantitative estimation of yeast population by simple gram stain smear revealed more than 70% of the cases had 3+ score. The isolates further screened for detection of -lactamases. Among the isolatedCandida sp,-lactamases was secreted byC. albicans, C. tropicalis, C. krusei andC. parapsilosis. Further, 46% of theCandida isolates were found to be produced 741–1110 mU/ml of-lactamases, suggesting that these enzyme would inactivate penicillin group of drugs and cause failure in the therapy directed against other diarrhoegenic bacteria.Abbreviation AAD antibiotic associated diarrhoea |
| |
| Keywords: | ![]("</a) /content/uur8r14191426812/xxlarge946.gif" alt=" beta" align=" MIDDLE" BORDER=" 0" >-lactamases Candida diarrhoea infants |
| 本文献已被 SpringerLink 等数据库收录！ |
|
