Isolation of 9-hydroxy-δ-tetradecalactone from lipid A of Pseudomonas diminuta and Pseudomonas vesicularis |
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| Authors: | Satoru Arata Tohru Hirayama Nobuhiko Kasai Takashi Itoh Akio Ohsawa |
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| Institution: | Department of Microbial Chemistry, School of Pharmaceutical Sciences, Showa University, Tokyo, Japan;Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Showa University, Tokyo, Japan |
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| Abstract: | Abstract A lipid component was isolated from the fatty acid fraction of acid hydrolysates of lipid A derived from Pseudomonas diminuta JCM 2788 and Pseudomonas vesicularis JCM 1477 lipopolysaccharide. By structural analysis of the lipid and its trimethylsilyl and acetyl derivatives by thin-layer chromatography, gas chromatography-mass spectrometry, mass spectrometry, infrared spectrometry and 13C-NMR, it was identified as 9-hydroxy-δ-tetradecalactone. |
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| Keywords: | Lipopolysaccharide Lipid A Hydroxy fatty acid |
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