狂犬病毒反向遗传学技术的研究及应用进展

反向遗传学技术是上世纪90年代在分子病毒学研究领域兴起的新技术，通常也被称为“病毒拯救”。综述了应用反向遗传学技术“拯救”狂犬病毒的主要技术体系以及反向遗传学技术在狂犬病毒致病机理、狂犬病毒疫苗及载体研究中的应用进展。

Advance in Reverse Genetic Technique for Rabies Virus

Reverse genetic technique, also named virus rescuing, was a new technique in molecular virology in last 90’s,which played a significant role in the study of rabies virus in these years.The reverse genetic technique for rabies virus rescuing and the research on pathogenesis,vaccine and vector of rabies virus with reverse genetics were reviewed.