Establishment and characterization of a bi-phenotypic leukemic cell line, NALM-19, from a patient with acute leukemia. |
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Authors: | Y Matsuo T Ariyasu T Adachi T Tsubota J Imanishi J Minowada |
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Institution: | Department of Internal Medicine, Okayama City Hospital. |
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Abstract: | Based on the immunophenotypic and genotypic findings, this acute leukemia cell line, designated NALM-19, is unique in that a partial expression of both B-cell and myeloid cell features are present in this single clonal leukemic cell population. It is noteworthy that two "normal" EB virus-transformed B cell lines, B239 and B240, (paired with NALM-19) were established from the same leukemic blood. |
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