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Qualitative and quantitative characteristics of the extracellular DNA delivered to the nucleus of a living cell |
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| Authors: | Vladimir A Rogachev Anastasia Likhacheva Oksana Vratskikh Lyudmila V Mechetina Tamara E Sebeleva Sergei S Bogachev Leonid A Yakubov Mikhail A Shurdov |
| Affiliation: | (1) Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, prosp. Koptyuga 2, Novosibirsk, 630090, Russia;(2) Panagenic International Inc, 2935 Byberry Road, Hatboro, PA 19040, USA;(3) Novosibirsk State University, ul. Pirogova 2, Novosibirsk, 630090, Russia;(4) OOO Panagen, ul, Choros-Gurkina 29, Gorno-Altaisk, 649000, Russia |
| Abstract: | BackgroundThe blood plasma and other intertissue fluids usually contain a certain amount of DNA, getting there due to a natural cell death in the organism. Cells of this organism can capture the extracellular DNA, whereupon it is delivered to various cell compartments. It is hypothesized that the extracellular DNA is involved in the transfer of genetic information and its fixation in the genome of recipient cell. |
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