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Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation |
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| Authors: | Pablo Largo-Barrientos Nuno Apóstolo Eline Creemers Zsuzsanna Callaerts-Vegh Jef Swerts Caitlin Davies Joseph McInnes Keimpe Wierda Bart De Strooper Tara Spires-Jones Joris de Wit Valerie Uytterhoeven Patrik Verstreken |
| Institution: | 1. VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium;2. KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven, Belgium;3. KU Leuven, mINT Animal Behavior Facility, Faculty of Psychology, Leuven, Belgium;4. Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK;5. UK Dementia Research Institute, University College London, London, UK |
| Abstract: | |
| Keywords: | Tau synapses synaptic plasticity working memory synaptic loss neuroinflammation microglia |
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