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White matter aging drives microglial diversity
Authors:Shima Safaiyan  Simon Besson-Girard  Tuğberk Kaya  Ludovico Cantuti-Castelvetri  Lu Liu  Hao Ji  Martina Schifferer  Garyfallia Gouna  Fumere Usifo  Nirmal Kannaiyan  Dirk Fitzner  Xianyuan Xiang  Moritz J Rossner  Matthias Brendel  Ozgun Gokce  Mikael Simons
Institution:1. Institute of Neuronal Cell Biology, Technical University Munich, 80802 Munich, Germany;2. German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany;3. Institute for Stroke and Dementia Research, University Hospital of Munich, LMU Munich, 81377 Munich, Germany;4. Department of Psychiatry, Ludwig-Maximilians-Universität, 80336 Munich, Germany;5. Department of Neurology, University of Göttingen, 37075 Göttingen, Germany;6. Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, 81377 Munich, Germany;7. Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany;8. Munich Cluster of Systems Neurology (SyNergy), 81377 Munich, Germany
Abstract:
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  • Keywords:microglia  aging  white matter  myelin  ApoE  Trem2
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