Novel poly(ADP-ribose) polymerase-1 inhibitors |
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Authors: | Dunn Derek Husten Jean Ator Mark A Chatterjee Sankar |
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Affiliation: | Cephalon, Inc., 145 Brandywine Parkway, West Chester, PA 19380 4245, USA. |
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Abstract: | Synthesis and activity of a series of 3-aroyl-derived analogs of novel pyrrolocarbazole 1 as poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors are disclosed. |
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