Characterization of the follicles in the intermediate lobe of the pituitary gland of the Mongolian gerbil (Meriones unguiculatus) |
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Authors: | Dr P Redecker |
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Institution: | (1) Institute of Anatomy, University of Münster, Münster, Germany;(2) Medizinische Hochschule Hannover, Abt. Anatomie I, Postfach 610180, D-3000 Hannover 61, Germany |
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Abstract: | Summary The Mongolian gerbil (Meriones unguiculatus) contains abundant follicles throughout the intermediate lobe (IL) of the pituitary gland in the adult animal. The mode of follicle formation, the nature of the follicle building cells and the distribution of follicles were investigated in semithin sections of the gerbil IL. The sections were stained conventionally, or immunohistochemically with antibodies directed against -melanocyte stimulating hormone ( - MSH). Follicular cells were constantly -MSH-negative, and resembled the marginal cells lining the hypophyseal cleft with regard to their cytological and immunohistochemical properties. Moreover, follicular cells appeared to be derived from strands of marginal cells that regularly invaginated deep into the IL. Both follicular and marginal cells often made up cellular clusters. This process coincided with follicle formation and the generation or transport of the colloidal content found inside follicles and the hypophyseal cleft. Although the non-secretory cells of the IL obviously constituted one major source of pituitary colloid in the gerbil, -MSH-positive secretory cells, which occasionally were found to be discharged into the cleft cavity, might contribute to the colloidal contents. |
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Keywords: | Pituitary Intermediate lobe follicles Immunohistochemistry -MSH" target="_blank">gif" alt="agr" align="BASELINE" BORDER="0">-MSH Agranular cells Meriones unguiculatus |
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