| 植物次生代谢途径的遗传操作 |
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| 引用本文： | 王晓云,夏循礼,黄凤兰,张寿文. 植物次生代谢途径的遗传操作[J]. 生物工程学报, 2012, 28(10): 1151-1163 |
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| 作者姓名： | 王晓云 夏循礼 黄凤兰 张寿文 |
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| 作者单位： | 江西中医学院药学院，江西省中药种质资源工程技术研究中心，江西 南昌 330004;江西中医学院药学院，江西省中药种质资源工程技术研究中心，江西 南昌 330004;内蒙古民族大学生命科学学院，内蒙古 通辽 028000;江西中医学院药学院，江西省中药种质资源工程技术研究中心，江西 南昌 330004 |
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| 基金项目： | 江西省教育厅科学技术研究项目 (No. GJJ11542)，国家十二五科技支撑计划 (No. 2011BAI04B01)，江西中医学院博士启动基金课题 (No. 530046) 资助。 |
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| 摘 要： | 植物次生代谢产物种类极其丰富,是人类的宝贵资源,这些产物及其合成途径相关酶具有空间特异性分布的特征。植物次生代谢途径的调控是个复杂的过程,受代谢产物水平、多酶复合物相互作用等多种因素的影响。通过遗传操作改造代谢过程,调控产物在植物体内的含量,是一条切实可行和具有广阔发展空间的途径。目前,改造植物次生代谢途径可以采取单基因操作和多基因操作两种策略进行。
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| 关 键 词： | 次生代谢产物 途径 调控 单基因操作 多基因操作 |
| 收稿时间： | 2012-03-15 |
Genetic modification of secondary metabolite biosynthesis in higher plants: a review |
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| Xiaoyun Wang,Xunli Xi,Fenglan Huang and Shouwen Zhang. Genetic modification of secondary metabolite biosynthesis in higher plants: a review[J]. Chinese journal of biotechnology, 2012, 28(10): 1151-1163 |
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| Authors: | Xiaoyun Wang Xunli Xi Fenglan Huang Shouwen Zhang |
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| Affiliation: | Jiangxi College of Traditional Chinese Medicine, Chinese Medicine Germplasm Resource Engineering Technology Research Center of Jiangxi Province, Nanchang 330004, Jiangxi, China;Jiangxi College of Traditional Chinese Medicine, Chinese Medicine Germplasm Resource Engineering Technology Research Center of Jiangxi Province, Nanchang 330004, Jiangxi, China;College of Life Science, Inner Mongolia University for the Nationalities, Tongliao 028000, Inner Mongolia, China;Jiangxi College of Traditional Chinese Medicine, Chinese Medicine Germplasm Resource Engineering Technology Research Center of Jiangxi Province, Nanchang 330004, Jiangxi, China |
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| Abstract: | Plants provide an immense reservoir of natural secondary metabolites. Secondary metabolites and those involved enzymes accumulate in various compartments in specific plant tissues. The biosynthesis of diverse groups of secondary metabolites is often complicated, tightly controlled via network interconnections, metabolite levels, metabolite channeling and multi-enzyme complexes, and so on. Secondary metabolite profiles could be genetically altered by two strategies, i.e. single gene modification and multiple gene modification; which thus has opened a feasible and prospective platform for secondary chemicals production in plant. |
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| Keywords: | secondary metabolite biosynthesis regulation single gene manipulation multiple gene manipulation |
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