Silver positivity of the NORs during embryonic development of Xenopus laevis |
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Authors: | A de Capoa F Pelliccia P Marlekaj A R Ciofiluzzatto M Buongiorno Nardelli |
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Institution: | Dipartimento di Genetica e Biologia Moleculare, Università di Roma, Rome, Italy |
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Abstract: | Bovine corneal endothelial cells adhered equally well to a variety of collagens (types I, III, IV and V) consistent with a role for fibronectin in this process. They did not exhibit a preferential binding to collagen type IV--as might be anticipated if laminin were to play a significant role in their adhesion. Inhibition studies with anti-fibronectin antibodies demonstrated the importance of endogenous fibronectin in the mediation of attachment. Consistent with this, binding did not appear to require the presence of exogenous protein, since cells bound to collagens equally well in the presence or absence of added fibronectin and binding was not stimulated by pretreatment of collagens with this protein. |
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Keywords: | To whom offprint requests should be sent Address: Institute of Genetics University of Rome Piazzale Aldo Moro 5 00185 Rome Italy |
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