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Synthesis and sar study of novel CCK-B antagonists |
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| Authors: | J.K. Padia G.L. Bolton D. Hill D.C. Horell B.D. Roth B.K. Trivedi |
| Affiliation: | Department of Medicinal Chemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lamberg Company, Ann Arbor, MI 48105 U.S.A. a Parke-Davis Neuroscience Research Centre, Hills Road, Cambridge CB2 2QB, UK. |
| Abstract: | The structure activity relationship and an efficient synthesis of N,N-disubstituted amides of -methyltryptophan via stable oxazolone derivatives 12a and 12b are described. |
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