Genetic improvement of glucose isomerase production inStreptomyces nigrificans by ultraviolet irradiation |
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| Authors: | K. Demnerová S. Pospíšil M. Blumauerová J. Káš |
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| Affiliation: | (1) Department of Biochemistry and Microbiology, Institute of Chemical Technology, 166 28 Prague 6;(2) Institute of Microbiology of the Czechoslovak Academy of Sciences, 142 20 Prague 4, Czechoslovakia |
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| Abstract: | Summary Glucose isomerase activity inStreptomyces nigrificans 3014, a producer of antibiotics of the chromomycin group., increased by 198 % as a result of a two-step improvement procedure including the selection of more active variants among antibiotic-producing isolates from population treated with ultraviolet light. |
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