Pachyovatamine,a bisbenzylisoquinoline alkaloid,and other alkaloids from Pachygone ovata |
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Authors: | M Uvais S Sultanbawa Subramaniam Sotheeswaran Sinnathamby Balasubramaniam Moustafa Abd El-kawi David J Slatkin Paul L Schiff |
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Institution: | 1. Department of Chemistry, University of Peradeniya, Peradeniya, Sri Lanka;2. Department of Pharmacognosy, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, U.S.A. |
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Abstract: | A new dibenzo-p-dioxin biphenyl bisbenzylisoquinoline alkaloid, pachyovatamine, has been isolated from an extract of the leaves and stems of Pachygone ovata from Sri Lanka. The alkaloid was characterized by a consideration of its physicochemical data and conversion to O-acetyltiliacorinine. Pachygonamine, N-methylpachygonamine and tiliamosine were also isolated from the same extract. |
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Keywords: | Menispermaceae leaves and stems pachyovatamine |
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