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Flavans from Zephyranthes flava
Authors:Shibnath Ghosal  Sushil K Singh  Radhey S Srivastava
Institution:Pharmaceutical Chemistry Research Laboratory, Department of Pharmaceutics, Banaras Hindu University, Varanasi 221005, India
Abstract:A new optically active flavan aglucone, 7-hydroxy-3′,4′-methylenedioxyflavan, and its 7-glucoside have been isolated from the bulbs of Zephyranthes flava, collected at flowering. Additionally, two known flavans, 7,4′-dihydroxy-3′-methoxyflavan and 7-methoxy-2′-hydroxy-4′,5′-methylenedioxyflavan, have been isolated for the first time from this species. The structures of these flavans have been established by comprehensive analyses (UV, IR, 1H NMR, 13C NMR, mass spectrometry, α]D) of the compounds and their acetates, and also by chemical correlation.
Keywords:Amaryllidaceae  7-hydroxy-3′  4′-methylenedioxyflavan  7  4′-dihydroxy-3′-methoxyflavan  7-methoxy-2′-hydroxy-4′  5′-methylenedioxyflavan  7-glucosyloxy-3′  4′-methylenedioxyflavan  
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