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Mevalonate decarboxylation in lemon grass leaves
Authors:R Lalitha  Rajan George  T Ramasarma
Institution:Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India
Abstract:The activity of mevalonate-5-pyrophosphate (MVAPP) decarboxylase was assayed in the extracts of green leaves of lemon grass. The enzyme was found to be exclusively cytosolic, had a pH optimum of 6.0 and had a specific requirement for ATP; Mg2+ was required and Mn2+ could replace it partially. The phenolic compounds, p-coumaric acid, protocatechuic acid, ferulic acid and phloroglucinol carboxylic acid inhibited the activity.
Keywords:Graminae  lemon grass  isoprenoid biosynthesis  mevalonate-5-pyrophosphate decarboxylase  
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