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Lupin alkaloids from flowers of Echinosophora koreensis
Authors:Isamu Murakoshi  Masanao Watanabe  Tomoyo Okuda  Eiji Kidoguchi  Joju Haginiwa  Shigeru Ohmiya  Hirotaka Otomasu
Affiliation:1. Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo, 142, Japan
Abstract:(?)-Methyl 12-cytisineacetate (2) was isolated from methanol extracts of fresh flowers of Echinosophora koreensis together with seven known lupin alkaloids. Ethyl 12-cytisineacetate (3) was also isolated from ethanol extracts of the same flowers. Compounds 2 and 3 were artifacts and (?)-12-cytisineacetic acid (4) is assumed to be the principal source of 2 and 3. The variations in alkaloid content during growth of the flowers and the seedlings were also examined.
Keywords:Leguminosae  flowers  lupin alkaloid  quinolizidine alkaloid  (?)-methyl 12-cytisineacetate  ethyl 12-cytisineacetate  (?)-12-cytisineacetic acid  (?)-cytisine  variation of alkaloid content.
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