Motors for fast axonal transport. |
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Authors: | T A Schroer |
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Affiliation: | Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218. |
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Abstract: | In neurons and other animal cells, membrane-bound vesicles course rapidly along cytoskeletal filaments to reach their destinations. Based on a variety of in vivo studies it is becoming clear that the microtubule-based motor, kinesin (and its relatives), drive vesicle movements in axons. Surprisingly, some axonal membranes have the capacity to move on both microtubules and actin filaments. |
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