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Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells
Authors:Sandra Acosta  Cinzia Lavarino  Raquel Paris  Idoia Garcia  Carmen de Torres  Eva Rodríguez  Helena Beleta  Jaume Mora
Affiliation:1. Developmental tumor biology laboratory, Hospital Sant Joan de Déu., Passeig Sant Joan de Déu, 2, 08950, Esplugues de Llobregat, Barcelona, Spain
Abstract:

Background  

Neuroblastic tumors (NBT) derive from neural crest stem cells (NCSC). Histologically, NBT are composed by neuroblasts and Schwannian cells. In culture, neuroblastic (N-), substrate-adherent (S-) and intermediate phenotype (I-) cell subtypes arise spontaneously.
Keywords:
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