An autosomal gene assignment in a marsupial: The gene for LDH-A is on chromosome 5 of the red kangaroo,Macropus rufus |
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| Authors: | Jennifer A Donald M A Adams |
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| Institution: | 1. Department of Genetics, University of Adelaide, 5000, Adelaide, S.A., Australia
3. Laboratory Animal Services, Institute of Medical and Veterinary Science, Frome Road, 5000, Adelaide, S.A., Australia
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| Abstract: | A number of somatic cell hybrids between red kangaroo (Macropus rufus) and mouse cells, which lose marsupial chromosomes, were found to express the kangaroo form of LDH-A. Concordance between the expression of marsupial LDH-A and the presence of chromosome 5 in the hybrid cells and selected subclones enabled the gene for LDH-A to be assigned to this chromosome. This is the first autosomal gene assignment in a marsupial and should prove important for chromosome mapping in the red kangaroo and in many other species of marsupials. |
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