Gratuitous induction of xanthine oxidase by 5,6-diaminouracil in continuously grown cells of Arthrobacter globiformis M4 |
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Authors: | Wouter J. Middelhoven Hans J. Brons Michaël W. Breedveld Ignace M. L. Suy Henk C. van der Plas |
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Affiliation: | (1) Department of Microbiology, Agricultural University, Wageningen, The Netherlands;(2) Department of Organic Chemistry, Agricultural University, Wageningen, The Netherlands |
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Abstract: | Summary 5,6-Diaminouracil (DAU), was found to be a gratuitous inducer of xanthine oxidase (XO) in Arthrobacter globiformis M4. Synthesis of urate oxidase was not induced by this compound. Preparation of a biocatalyst rich in XO could be achieved by exposing continuously grown cells to low concentrations of DAU. |
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