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Gratuitous induction of xanthine oxidase by 5,6-diaminouracil in continuously grown cells of Arthrobacter globiformis M4
Authors:Wouter J. Middelhoven  Hans J. Brons  Michaël W. Breedveld  Ignace M. L. Suy  Henk C. van der Plas
Affiliation:(1) Department of Microbiology, Agricultural University, Wageningen, The Netherlands;(2) Department of Organic Chemistry, Agricultural University, Wageningen, The Netherlands
Abstract:Summary 5,6-Diaminouracil (DAU), was found to be a gratuitous inducer of xanthine oxidase (XO) in Arthrobacter globiformis M4. Synthesis of urate oxidase was not induced by this compound. Preparation of a biocatalyst rich in XO could be achieved by exposing continuously grown cells to low concentrations of DAU.
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