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Effects of Estradiol and Testosterone in the Hagfish Eptatretus burgeri
Authors:Kazuhiko Tsuneki
Abstract:Effects of exogenous estradiol and testosterone on the gonad and pituitary were examined in the hagfish. Estradiol caused degeneration of the ovary. Testosterone had no effect on the ovary. Neither steroid had a significant effect on the testis. Neither estradiol nor testosterone provoked a conspicuous change in adenohypophysial cells. Therefore, a feedback mechanism between gonadal steroids and gonadotropin either does not exist or plays a very minor role. The degeneration of the ovary may be due to a pharmacological effect of estradiol.
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