Parallel and interrelated neural systems underlying adaptive navigation

The ability to process in parallel multiple forms of sensoryinformation, and link sensory-sensory associations to behavior,presumably allows for the opportunistic use of the most reliableand predictive sensory modalities in diverse behavioral contexts.Evolutionary considerations indicate that such processing mayrepresent a fundamental operating principle underlying complexsensory associations and sensory-motor integration. Here, wesuggest that animal navigation is a particularly useful modelof such opportunistic use of sensory and motor information becauseit is possible to study directly the effects of memory on neuralsystem functions. First, comparative evidence for parallel processingacross multiple brain structures during navigation is providedfrom the literatures on fish and rodent navigation. Then, basedon neurophysiological evidence of coordinated, multiregionalprocessing, we provide a neurobiological explanation of learningand memory effects on neural circuitry mediating navigation.