Nitric oxide synthase-containing neurons in rat parasympathetic, sympathetic and sensory ganglia: a comparative study |
| |
Authors: | Per Alm Bengt Uvelius J?rgen Ekstr?m Bo Holmqvist Bengt Larsson and Karl-Erik Andersson |
| |
Institution: | (1) Department of Pathology, University of Lund, Lund University Hospital, S-221 85 Lund, Sweden;(2) Department of Urology, University of Lund, Lund University Hospital, S-221 85 Lund, Sweden;(3) Department of Zoology, University of Lund, Lund University Hospital, S-221 85 Lund, Sweden;(4) Department of Clinical Pharmacology, University of Lund, Lund University Hospital, S-221 85 Lund, Sweden;(5) Department of Pharmacology, University of Gothenburg, Sweden |
| |
Abstract: | Summary In rats, the distribution of nerve structures staining for NADPH-diaphorase, and showing immunoreactivities for nitric oxide
synthase (NOS), tyrosine hydroxylase and various neuropeptides was studied in sensory ganglia (dorsal root, nodose and trigeminal
ganglia), in sympathetic ganglia (superior cervical, stellate, coeliac-superior and inferior mesenteric ganglia), parasympathetic
ganglia (sphenopalatine, submandibular, sublingual and otic ganglia), and in the mixed parasympathetic/ sympathetic ganglia
(major pelvic ganglia). The coincidence of neuronal cell bodies with strong NOS-immunoreactivity and strong NADPH diaphorase
reactivity was almost total. The relative proportions of NOS-immunoreactive nerve cell bodies were largest in parasympathetic
ganglia and major pelvic ganglia followed by sensory ganglia. In sympathetic ganglia no NOS-immunoreactive neuronal cell bodies
could be detected. In parasympathetic and major pelvic ganglia, there was a very significant neuronal co-localization of immunoreactivities
for NOS and vasoactive intestinal polypeptide (VIP). This was almost total in major pelvic ganglia, in which NOS-/VIP-immunoreactive
nerve cell bodies were separate from sympathetic (tyrosine hydroxylase-/neuropeptide Y-immunoreactive), suggesting that NOS-/VIP-immuno-reactive
neurons might also be parasympathetic. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|