Effect of neurotensin injections into caudate nuclei on realization and extinction of conditioned motor reflex in rats

It was shown that neurotensin microinjections into the caudate nuclei facilitated of a conditioned reflex but not affected its realization. Besides, neurotensin was shown to have a positive aftereffect on extinction. Motor activity of rats in the "open field" was augmented after neurotensin administration. A conclusion was drawn that the functional effect of neurotensin administration into the caudate nuclei is connected with the normalization of the motivational and emotional state of an animal rather than with the regulation of the motor function.