Holding the line on hepatic fat |
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| Authors: | Saltiel Alan R |
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| Institution: | Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109 |
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| Abstract: | When chronically elevated, insulin increases hepatic lipogenesis and VLDL synthesis. However, the hormone reduces liver lipids when acutely elevated. Work in this issue of Cell Metabolism (Najjar at al., 2005) suggests a new mechanism for the inhibition of the rate-limiting enzyme in liver, fatty acid synthase. |
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