The adenine nucleotide translocator in foetal, suckling and adult rat liver mitochondria |
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| Authors: | J K Pollack R Sutton |
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| Institution: | Department of Histology & Embryology, University of Sydney, Sydney, N.S.W. 2006, Australia;Institut für Physiologische Chemie und Physikalische Biochemie der Universität München, 8000 München 2, Germany |
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| Abstract: | The adenine nucleotide content of rat liver mitochondria was shown to increase significantly after birth. On the other hand, it was found that the ligand-binding properties of the adenine nucleotide translocator were essentially the same in foetal, suckling and adult rat liver mitochondria. These results are compatible with the proposal that the accumulation of adenine nucleotides which occurs during mitochondrial biogenesis and maturation is effected by a pathway different from the adenine nucleotide translocator. |
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