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CAF-like state in primary skin fibroblasts with constitutional BRCA1 epimutation sheds new light on tumor suppressor deficiency-related changes in healthy tissue |
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| Authors: | Anna Etzold Danuta Galetzka Eva Weis Oliver Bartsch Thomas Haaf Claudia Spix |
| Institution: | 1. Institute of Human Genetics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany;2. Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany;3. Institute of Medical Biometry, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany |
| Abstract: | |
| Keywords: | BRCA1 cancer-associated fibroblasts CAFs tumor-suppressor deficiency cancer predisposition epimutation mosaic promoter methylation primary fibroblasts |