| Abstract: | Mouse NK/LY lymphoma cells were modified by Con A or Vibrio cholerae neuraminidase (VCN). Severe damage of the modified cells was not revealed by either supravital staining or light microscopy. Ultrastructural signs of metabolic lowering in the Con-A-treated cells were determined. Some increase in electrophoretic mobility of Con-A-modified cells was found, along with its decrease in VCN-modified cells. The decrease in the pool of proliferating cells was determined in both the types of modification, being more evident in the Con-A-modified material. A marked tumorigenic decrease of Con-A-modified cells was fixed. |
