Selenium, boron, and germanium deficiency in the etiology of Kashin-Beck disease |
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Authors: | Xu Peng Zeng Lingxia G N Schrauzer Guo Xiong |
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Institution: | (1) Institute of Endemic Bone Diseases, Xi’an Medical University, 710061 Xi’an, P. R. China;(2) Biological Trace Element Research Institute, 92121 San Diego, CA |
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Abstract: | Concentrations of selenium (Se), boron (B), and germanium (Ge) were determined in scalp hair of children with Kashin-Beck
disease (KBD), in healthy children in KBD-disease endemic areas, and in healthy children in non-KBD areas. Mean Se, B, and
Ge concentrations were low in children with KBD; in hair of healthy children in KBD areas, Se levels were normal but B and
Ge levels were lower than in KBD-free areas. The hair levels of B and Ge were unaffected by selenium supplementation. It is
suggested that B and Ge deficiency may be contributing factors in the etiology of KBD. |
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Keywords: | Kashin-Beck disease scalp hair boron germanium selenium |
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