Space flight effects on haemopoietic stem cells of the bone marrow of rats |
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Authors: | A. Vacek,L. Tkadle ek,V. N. Shvets,A. Bartoni kov,S. Viklick,D. Rotkovsk,L. V. Serova,T. V. Michurina&dagger |
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Affiliation: | Institute of Biophysics, Czechoslovak Academy of Sciences, Brno, Czechoslovakia;*Institute of Medical and Biological Problems, Ministry of Health of the U.S.S.R., Moscow;†Institute of Biology of Development, Academy of Sciences, of the U.S.S.R., Moscow, U.S.S.R. |
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Abstract: | Abstract. Changes in the number of haemopoietic stem cells (CFU-s) were studied in rats during the recovery day and selected post-recovery days after an 18–19-day flight on biosatellites Cosmos 936 and Cosmos 1129 . There was a decrease in the CFU-s number of the bone marrow of rats on the recovery day. On the 6th day post-recovery the CFU-s number was still depressed, while on the 25th day post-recovery it was elevated above control value. The differentiation ratio of transplanted bone marrow cells was not altered by space flight. |
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