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Impact of dual-baculovirus infection on the Sf9 insect cell transcriptome during rAAV production using single-cell RNA-seq |
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| Authors: | Nikolaus Virgolini Marco Silvano Ryan Hagan Ricardo Correia Paula M. Alves Colin Clarke António Roldão Inês A. Isidro |
| Affiliation: | 1. IBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal;2. IBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal ITQB NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal;3. National Institute for Bioprocessing Research and Training, Dublin, Ireland School of Chemical and Bioprocess Engineering, University College Dublin, Dublin, Belfield, Ireland;4. National Institute for Bioprocessing Research and Training, Dublin, Ireland |
| Abstract: | |
| Keywords: | adeno-associated virus baculovirus infection BEVS biopharmaceutical production gene therapy vector RNA-seq |