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Double-reporter-guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527
Authors:Yue Shi  Jinyao Zhang  Zheng Ma  Yongyong Zhang  Andreas Bechthold  Xiaoping Yu
Institution:1. Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang Province, China;2. Institute for Pharmaceutical Sciences, Pharmaceutical Biology and Biotechnology, University of Freiburg, Freiburg, Germany
Abstract:
Keywords:activation of silent gene cluster  double-reporter-guided  oxytetracycline  ribosome engineering  Streptomyces rimosus M527
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