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MicroRNA与肠易激综合征的相关性研究进展
引用本文:赵泓舒,陈民利. MicroRNA与肠易激综合征的相关性研究进展[J]. 中国实验动物学杂志, 2012, 0(9): 68-71,86
作者姓名:赵泓舒  陈民利
作者单位:浙江中医药大学动物实验研究中心/比较医学研究中心,杭州310053
基金项目:[基金项目]浙江省教育厅重大科技攻关项目(ZD2009004);浙江省卫生高层次创新人才培养工程项目.
摘    要:肠易激综合征(IBS)是一种常见的病因不明的紊乱性疾病。在IBS患者的血液微泡和结肠组织中存在一些失调的microRNA(miRNA)。对于miRNA的研究,最初阶段可能作为一种新的途径用来进一步了解IBS的病理生理学特征,而最终将使用miRNA作为新的策略思考IBS的诊断和治疗方法。目前,miRNA在IBS发病机制中的作用的研究报道甚少。本文主要对miRNA在IBS方面的研究进行综述。

关 键 词:肠易激综合征  MicroRNA

Overview of Relevance between MicroRNA and Irritable Bowel Syndrome
ZHAO Hong-shu,CHEN Min-li. Overview of Relevance between MicroRNA and Irritable Bowel Syndrome[J]. Chinese Journal of Laboratory Animal Science, 2012, 0(9): 68-71,86
Authors:ZHAO Hong-shu  CHEN Min-li
Affiliation:(Laboratory Animal Research Center, Zhejiang Chinese Medical University, Hangzhou 310053, China)
Abstract:The irritable bowel syndrome (IBS) is a common disorder of unknown etiology. A group of dysregulated microRNAs (miRNAs) in blood microvesicles and in colon tissue have been identified in IBS patients. Research on miRNA, first phase may serve as a new way to further understand the pathophysiology of IBS characteristics, and eventually will leads us to use new strategy for diagnosis and treatment of IBS method by using miRNAs. Currently, there is not a lot of study with the role of miRNA in IBS. This paper summarize the work about miRNA on IBS.
Keywords:Irritable bowel syndrome  MicroRNA
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