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Evaluation of a critical process parameter: oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis |
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| Authors: | Streefland Mathieu van de Waterbeemd Bas Kint Joeri van der Pol Leo A Beuvery E Coen Tramper Johannes Martens Dirk E |
| Affiliation: | Netherlands Vaccine Institute (NVI), Unit Research and Development, PO Box 457, 3720 AL Bilthoven, The Netherlands. mathieu.streefland@nvi-vaccin.nl |
| Abstract: | |
| Keywords: | process analytical technology PAT Bordetella pertussis vaccine cultivation biopharmaceutical DNA microarray virulence oxygen limitation dissolved oxygen concentration |
| 本文献已被 PubMed 等数据库收录！ | |