Biosynthesis of nucleic acid purines in Mycobacterium tuberculosis H37Rv |
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| Authors: | V G Malathi and T Ramakrishnan |
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| Institution: | Pharmacology Laboratory, Indian Institute of Science, Bangalore 12, India |
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| Abstract: | 1. The biosynthesis of nucleic acid purine in Mycobacterium tuberculosis H(37)R(v) has been studied by using (14)C-labelled precursors. 2. The results indicate that C-2 and C-8 of the purine ring are derived most efficiently from serine and glycine and not from formate. 3. (14)C]Methionine is not incorporated into the ureide carbon atoms of the purine ring. |
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