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Isoflavone glycosides from Derris scandens |
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| Authors: | Rukachaisirikul Vatcharin Sukpondma Yaowapa Jansakul Chaweewan Taylor Walter C |
| Affiliation: | a Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkla, 90112, Thailand b Department of Physiology, Faculty of Science, Prince of Songkla University, Hat Yai, Songkla, 90112, Thailand c School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia |
| Abstract: | Five isoflavone glycosides, named derriscandenosides A–E (1–5), were isolated from the stems of Derris scandens, together with ten known compounds comprising one isoflavone, two benzoic acid derivatives, three glucosyl isoflavones and four rhamnosyl-(1→6)-glucosyl isoflavones. The structures of the glycosides were assigned on the basis of spectroscopic data, especially of the acetate derivatives. Three known rhamnosyl-(1→6)-glucosyl isoflavones isolated from a crude fraction were retested for hypotensive activity with varying results. |
| Keywords: | Derris scandens Leguminosae Isoflavone glycosides Isoflavone glucosides Rhamnosyl-(1→6)-glucosyl isoflavones Hypotensive activity |
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