The genome sequence of a reassortant bluetongue virus serotype 3 from India |
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Authors: | Maan Narender S Maan Sushila Guimera Marc Nomikou Kyriaki Morecroft Elizabeth Pullinger Gillian Belaganahalli Manjunatha N Mertens Peter P C |
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Institution: | Vector-borne Diseases Programme, Institute for Animal Health, Pirbright, Woking Surrey, United Kingdom. |
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Abstract: | All 10 genome segments (Seg-1 to 10-a total of 19,188 bp) were sequenced from a strain of bluetongue virus serotype 3 (BTV-3) from India (strain IND2003/08). Sequence comparisons showed that nine of the genome segments from this virus group with other eastern topotype strains. Genome Seg-2 and Seg-6 group with eastern BTV-3 strains from Japan. However, Seg-5 (the NS1 gene) from IND2003/08 belongs to a western lineage, demonstrating that IND2003/08 is a reassortant between eastern and western topotype bluetongue viruses. This confirms that western BTV strains have been imported and are circulating within the subcontinent. |
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