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Diet,Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites
Authors:Shiho Fujisaka  Julian Avila-Pacheco  Marion Soto  Aleksandar Kostic  Jonathan M Dreyfuss  Hui Pan  Siegfried Ussar  Emrah Altindis  Ning Li  Lynn Bry  Clary B Clish  C Ronald Kahn
Institution:1. Section of Integrative Physiology and Metabolism, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02215, USA;2. First Department of Internal Medicine, University of Toyama, Toyama 930-0194, Japan;3. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;4. Department of Microbiology and Immunobiology, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02215, USA;5. Bioinformatics Core, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02215, USA;6. Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA;7. Institute for Diabetes and Obesity, Helmholtz Zentrum München, 85764 Neuherberg, Germany;8. Center for Clinical and Translational Metagenomics. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA
Abstract:
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  • Keywords:gut microbiome  serum metabolomics  cecal metabolomics  obesity  diabetes  serum lipids  TMAO  bile acids  antibiotics  diet
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