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0Adipose-derived stem cells: Implications in tissue regeneration
Authors:Wakako Tsuji  J Peter Rubin  Kacey G Marra
Abstract:Adipose-derived stem cells(ASCs) are mesenchymal stem cells(MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differ-entiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs dam-aged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration.
Keywords:Mesenchymal stem cells  Adipose-derived stem cells  Differentiation  Growth factors  Tissue engi-neering  Clinical trials
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