| 人卵泡促性腺激素释放肽（hF－GRP）的STM研究 |
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| 引用本文： | 吴宏伟,林克椿.人卵泡促性腺激素释放肽（hF－GRP）的STM研究[J].生物物理学报,1996,12(2):179-182. |
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| 作者姓名： | 吴宏伟 林克椿 |
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| 作者单位： | 北京医科大学生物物理系,北京 100083 |
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| 摘 要： | 人卵泡促性腺激素释放肽（ｈＦ－ＧＲＰ）为一只含１４个氨基酸的多肽类激素，我们已经用２Ｄ－ＮＭＲ技术测定了它的溶液构象，本文又用ＳＴＭ技术观察了ｈＦ－ＧＲＰ单层铺展时的分子图象，测得其分子大小约为２．４ｎｍ，并用２Ｄ－ＮＭＲ结果较好地解释了所得的图象。
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| 关 键 词： | 人卵泡 促性腺激素 释放肽 hF－GRP STM |
CONFORMATIONAL STUDY OF HUMAN FOLLICULAR GONADOTROPIN-RELEASING PEPTIDE (hF-GRP)BY STM |
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| Abstract: | hF-GPR deposital on a highly oriented pyrolytic graphite(HOPG)substrate,has been observed by STM under ambient conditions.A single layer packed structure of hF-GRP molecules was imaged for the first time.About 2. 4nm in length was found in the STM image of hF-GRP molecule.The conformational properties of hF-GRP molecules on the STM image agree well with the results of 2D-NMR experiment. |
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| Keywords: | STM hF-GRP 2D-NMR |
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