| 基于螺旋区随机堆积的RNA二级结构预测 |
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| 引用本文： | 李伍举,吴加金.基于螺旋区随机堆积的RNA二级结构预测[J].生物物理学报,1996,12(2):213-218. |
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| 作者姓名： | 李伍举 吴加金 |
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| 作者单位： | 军事医学科学院基础医学研究所 |
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| 摘 要： | 提出了基于螺旋区随机堆积的ＲＮＡ二级结构预测算法，包括三个步骤：１．根据螺旋区定义，找出所有可能螺旋区；２进行螺旋区随机堆积，形成一定数目的ＲＮＡ二级结构；３．统计处理，推测ＲＮＡ可能折叠方式。最后以酵母Ｐｈｅ－ｔＲＮＡ为例来说明方法的可行性。
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| 关 键 词： | RNA二级结构，随机堆积，预测 |
PREDICTION OF RNA SECONDARY STRUCTURE BASED ON RANDOM STACKING OF HELICAL REGIONS |
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| Li Wuju,Wu Jiajin.PREDICTION OF RNA SECONDARY STRUCTURE BASED ON RANDOM STACKING OF HELICAL REGIONS[J].Acta Biophysica Sinica,1996,12(2):213-218. |
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| Authors: | Li Wuju Wu Jiajin |
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| Abstract: | We present a computer method to predict RNA secondary structures which is based on helical regions random stacking and consists of three steps:1.List all possible helical regions.2.creat a certain number of RNA secondary structures,using helical regions random stacking,and 3 infer the mode of RNA possible folding according to the results obtained from statistical analysis.Finally,we take yeast Phe-tRNA as an example to illustrate the reliability of the algorithm. |
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| Keywords: | RNA secondary structure Helical regions random stacking Prediction |
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