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Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration
Institution:1. Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;2. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;3. Laboratory for Circuit and Behavioral Physiology, RIKEN Center for Brain Science, Wakoshi, Saitama 351-0198, Japan;4. McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;5. Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan;6. Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Abstract:
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  • Keywords:Alzheimer’s disease  cross-hemispheric circuit  interhemispheric circuit  CH neurons  PV interneurons  gamma oscillations  theta oscillations  novelty discrimination
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