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Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions
Affiliation:1. State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, Beijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China;2. State Key Laboratory of Membrane Biology, Peking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, College of Future Technology, Peking University, Beijing 100871, China;3. Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Science, Tsinghua University, Beijing 100084, China
Abstract:
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  • Keywords:Piezo1  mechano-gated channel  astrocyte  adult neurogenesis  mechanotransduction  calcium  ATP  LTP  learning  memory
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