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Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction
Institution:1. Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, MA 02138, USA;2. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;3. The Rowland Institute at Harvard, Harvard University, Cambridge, MA 02138, USA;4. Swiss Federal Institute of Technology Lausanne, Geneve 1202, Switzerland;5. Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA;6. Wallace H. Coulter Department of Biomedical Engineering, Emory School of Medicine, Georgia Institute of Technology, Atlanta, GA 30322, USA
Abstract:
Keywords:novelty  dopamine  reinforcement learning  avoidance  neophobia  initialization  uncertainty  threat  prediction  threat prediction error  tail of the striatum
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