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Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition
Affiliation:1. Department of Psychiatry of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China;2. Liangzhu Laboratory, The MOE Frontier Research Center of Brain & Brain-Machine Integration, Zhejiang University School of Brain Science and Brain Medicine, 1369 West Wenyi Road, Hangzhou 311121, China;3. Research Unit of Mitochondria in Brain Diseases, Chinese Academy of Medical Sciences, PKU–Nanjing Institute of Translational Medicine, Nanjing 211500, China;4. Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA, USA;5. Institutes of Brain Science, Department of Neurology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China;6. Center for Brian Science and Brain-Inspired Intelligence, Guangdong-Hong Kong-Macao Greater Bay Area, Guangzhou 510515, China;7. Research Units of Brain Mechanisms Underlying Emotion and Emotion Disorders, Chinese Academy of Medical Sciences, Beijing, 100730, China;8. Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310058, China;9. Chuanqi Research and Development Center of Zhejiang University, Hangzhou 310058, China
Abstract:
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  • Keywords:social dominance  social competition  tube test  medial prefrontal cortex  microcircuit dynamics  PV neurons  VIP neurons  SOM neurons  disinhibition  E-I balance
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